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Gene Symbol POLD2
Gene Description POLD2, DNA polymerase delta 2, accessory subunit, is one of four subunits that form the DNA polymerase delta holoenzyme, which mediates DNA replication (PMID: 27320729) and repair (PMID: 31954770). Amplification and/or overexpression of POLD2 has been observed in ovarian cancer (PMID: 21079801, PMID: 25875127), osteosarcoma (PMID: 31216829), esophageal squamous cell carcinoma (PMID: 30695860), and bladder urothelial carcinoma (PMID: 30038717).
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