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Gene Symbol DDIT4
Synonyms Dig2 | REDD-1 | REDD1
Gene Description DDIT4, DNA damage inducible transcript 4, is a hypoxia induced inhibitor of MTORC1 (PMID: 20166753). Decreased expression of DDIT4 has been observed in breast cancer (PMID: 18198340), while increased expression has been associated with poor prognosis in acute myeloid leukemia (PMID: 31755224).
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