Gene Detail

Gene Symbol DDIT4
Synonyms Dig2 | REDD-1 | REDD1
Gene Description DDIT4, DNA-damage-inducible transcript 4, (REDD1) is a hypoxia induced inhibitor of MTORC1 (PMID: 20166753). Decreased expression of DDIT4 (REDD1) has been observed in breast cancers and loss of DDIT4 promoted tumorigenicity in mouse models (PMID: 18198340).
Entrez Id 54541
Chromosome 10
Map Location 10q22.1
Canonical Transcript NM_019058

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