Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol PPEF1
Synonyms PP7 | PPEF | PPP7C | PPP7CA
Gene Description PPEF1, protein phosphatase with EF-hand domain 1, is a serine-threonine phosphatase that contains an EF hand domain (PMID: 19662497) and may play a role in regulating Tp53 induction of apoptosis in response to genotoxic stress (PMID: 28051100). Overexpression of Ppef1 has been observed in colorectal, breast, prostate, liver, and lung cancers (PMID: 28051100).


Additional content available in CKB BOOST