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Gene Symbol PPP2R1B
Synonyms PP2A-Abeta | PR65B
Gene Description PPP2R1B, protein phosphatase 2 regulatory subunit Abeta, is a scaffold subunit of the major serine-threonine phosphatase PP2A, which has roles in cell signaling, proliferation, differentiation, and apoptosis (PMID: 23454242). Alterations of PPP2R1B have been observed in lung, colon, and breast cancer (PMID: 9765152, PMID: 10713707) and is regulated by exosomal miR-200c in tongue squamous cell carcinoma (PMID: 32310826).
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