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Gene Symbol SOX6
Gene Description SOX6, SRY-box 6, is a member SRY superfamily of transcription factors and plays a role in regulation of cell proliferation and differentiation (PMID: 21495113, PMID: 23731550). Expression of SOX6 has been demonstrated to be altered in several tumor types, including glioma, esophageal squamous cell carcinoma, and hepatocellular carcinoma (PMID: 15696967, PMID: 21084391, PMID: 23731550), and a SOX6-BRAF fusion has been identified in atypical Spitz tumor (PMID: 23890088).
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