Gene Detail

Gene Symbol ZCCHC8
Gene Description ZCCHC8, zinc finger, CCHC domain containing 8, is a zinc-knuckle protein that forms a subunit of the Nuclear Exosome Targeting (NEXT) complex, which may function in regulation of RNA metabolism (PMID: 21855801, PMID: 25852104). ZCCHC8-ROS1 fusions have been identified in glioblastoma mulitforme and spitzoid tumors (PMID: 27121553, PMID: 24445538).
Entrez Id 55596
Chromosome 12
Map Location 12q24.31
Canonical Transcript NM_017612

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