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Gene Symbol RNPC3
Synonyms IGHD5 | RBM40 | RNP | SNRNP65
Gene Description RNPC3, RNA binding region (RNP1, RRM) containing 3, is a component of the U12-dependent splicesome that catalyzes pre-mRNA splicing, and regulates cellular integrity and embryonic development (PMID: 30254136). A fusion of RNPC3 with ROS1 has been observed in non-small cell lung cancer (PMID: 27370605), and the expression of RNPC3 has been identified in cancer-associated scleroderma (PMID: 27821747).


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