Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Gene Description||TMEM127, transmembrane protein 127, acts as part of a lysosomal complex that plays a role in regulation of mTORC1 signaling (PMID: 21447639, PMID: 29547888). TMEM127 germline mutations are associated with pheochromocytoma and paraganglioma (PMID: 20154675, PMID: 20923864, PMID: 22419703), and have also been identified in renal cell carcinoma (PMID: 24334765).|