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Gene Symbol PRKAR1A
Synonyms ACRDYS1 | ADOHR | CAR | CNC | CNC1 | PKR1 | PPNAD1 | PRKAR1 | TSE1
Gene Description PRKAR1A, protein kinase cAMP-dependent type I regulatory subunit alpha, is a major component of Pka which mediates cAMP-dependent signaling (PMID: 26042218). Inactivation of PRKAR1A is associated with the familial syndrome of Carney complex (PMID: 20301463, PMID: 30699069), adrenocortical tumors (PMID: 26042218), and melanoma (PMID: 32118628).


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