Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol RNF130
Synonyms G1RZFP | GOLIATH | GP
Gene Description RNF130, ring finger protein 130, is an E3 ligase protein that belongs to the superfamily of GRAIL transmembrane proteins and plays a role in ubiquitination (PMID: 16549277). Elevated expression of RNF130 has been observed in Barrett esophagus and esophageal adenocarcinoma (PMID: 25228972), and a RNF130-BRAF fusion has been identified in pilocytic astrocytoma (PMID: 25040262).


Additional content available in CKB BOOST