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Gene Symbol RNF130
Synonyms G1RP | G1RZFP | GOLIATH | GP
Gene Description RNF130, ring finger protein 130, is an E3 ligase protein that belongs to the superfamily of GRAIL transmembrane proteins and plays a role in ubiquitination (PMID: 16549277). Elevated expression of RNF130 has been observed in Barrett esophagus and esophageal adenocarcinoma (PMID: 25228972), and a RNF130-BRAF fusion has been identified in pilocytic astrocytoma (PMID: 25040262).
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