Gene Detail


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Gene Symbol PBK
Synonyms CT84 | HEL164 | Nori-3 | SPK | TOPK
Gene Description PBK, PDZ binding kinase, is a serine/threonine kinase that belongs to the MAPKK family, which plays a role in mitosis and cell proliferation (PMID: 25575812, PMID: 25881543, PMID: 26081429). PBK overexpression has been demonstrated in several solid and hematological tumor types (PMID: 25881543, PMID: 27334838, PMID: 30855480) and may confer resistance to radiotherapy in glioblastoma (PMID: 31874375).
Additional content available in CKB BOOST