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Gene Symbol PTPRD
Synonyms HPTP | HPTPD | HPTPDELTA | PTPD | R-PTP-delta | RPTPDELTA
Gene Description PTPRD, protein tyrosine phosphatase receptor type D, is a transmembrane protein (PMID: 30208623) that plays a role in cell growth, adhesion, migration, survival (PMID: 25113440), and regulates neurodevelopment (PMID: 31914388). PTPRD is inactivated in a variety of solid tumors (PMID: 19478061), including advanced stage gastric cancer (PMID: 31805999, PMID: 31041642), laryngeal squamous cell carcinoma (PMID: 28345455), and copy number alterations have been reported in Ewing's sarcoma (PMID: 31072725).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5789 9 9p24.1-p23 NM_002839 Tumor suppressor (PMID: 30606230)
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