Gene Detail

Gene Symbol PTPRK
Synonyms R-PTP-kappa
Gene Description PTPRK, protein tyrosine phosphatase, receptor type K, is a signaling molecule that negatively regulates EGFR signaling thereby playing a role in cell invasion, migration, and proliferation (PMID: 23552869, PMID: 25609089). Decreased expression and molecular alterations of PTPRK have been observed in breast and colon cancer (PMID: 23552869, PMID: 22895193).
Entrez Id 5796
Chromosome 6
Map Location 6q22.33
Canonical Transcript NM_001291984


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