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Gene Symbol RAD51B
Synonyms R51H2 | RAD51L1 | REC2
Gene Description RAD51B, RAD51 paralog B, plays a role in homologous recombination repair of double-strand DNA breaks (PMID: 21821141, PMID: 32098697). RAD51B mutations are associated with susceptibility to breast cancer (PMID: 24139550, PMID: 29255180) and overexpression has been correlated with a favorable prognosis in non-small cell lung cancer (PMID: 29207658) and a poor prognosis in gastric cancer (PMID: 27651161).
Additional content available in CKB BOOST