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Gene Symbol RANBP2
Synonyms ADANE | ANE1 | IIAE3 | NUP358 | TRP1 | TRP2
Gene Description RANBP2, RAN binding protein 2, plays a role in appropriate assembly of the nuclear envelope and ensures proper progression of mitosis and chromosomal segregation (PMID: 24113188). A RANBP2-ALK fusion has been identified in acute myelomonocytic leukemia, diffuse large B-cell lymphoma, and inflammatory myofibroblastic tumor (PMID: 24613277, PMID: 24470379, PMID: 12661011), and a RANBP2-FGFR1 fusion has been identified in myeloid neoplasm (PMID: 23041776).
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