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Gene Symbol RARA
Synonyms NR1B1 | RAR | RARalpha
Gene Description RARA, retinoic acid receptor alpha, plays a role in regulating gene transcription and is involved in the differentiation of hematopoietic cells (PMID: 21911359). RARA fusions with multiple gene partners are frequently observed in hematological cancers (PMID: 31447065, PMID: 30292835, PMID: 32242976), including the PML-RARA fusion in acute promyelocytic leukemia (PMID: 15103387, PMID: 32182684, PMID: 32033928).
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