Gene Detail

Gene Symbol APOBEC3G
Synonyms A3G | ARCD | ARP-9 | ARP9 | bK150C2.7 | CEM-15 | CEM15 | dJ494G10.1 | MDS019
Gene Description APOBEC3G, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G, is a cytidine deaminase that induces C-to-U mutations in DNA, functioning in host defense against retroviruses and to inhibit retrotransposons (PMID: 22001110). APOBEC3G expression correlates with poor prognosis in colon cancer patients with hepatic metastasis (PMID: 24753761) and overexpression has been observed in uterine cervical intraepithelial neoplasia (PMID: 28590025).
Entrez Id 60489
Chromosome 22
Map Location 22q13.1
Canonical Transcript NM_021822

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