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Gene Symbol RPA1
Synonyms HSSB | MST075 | PFBMFT6 | REPA1 | RF-A | RP-A | RPA70
Gene Description RPA1, replication protein A 70 kDa DNA-binding subunit, is part of a heterotrimeric protein complex, which functions in DNA replication, homologous recombination, excision repair (PMID: 29477843), and telomere maintenance (PMID: 29665433). Overexpression of Rpa1 is associated with poor prognosis in hepatocellular carcinoma (PMID: 29477843) and esophageal carcinoma (PMID: 26824734).
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