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Gene Symbol RPE65
Synonyms BCO3 | LCA2 | mRPE65 | p63 | rd12 | RP20 | sRPE65
Gene Description RPE65, retinoid isomerohydrolase RPE65, encodes an enzyme that plays a role in the isomerization of retinol in the rod and cone visual cycle, and is necessary in order to maintain normal vision (PMID: 15825812, PMID: 16116091, PMID: 30002120). Decreased RPE65 expression has been observed in melanoma cells (PMID: 24433184).
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