Gene Detail
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| Gene Symbol | CLIP1 | ||||||||||
| Synonyms | CLIP | CLIP-170 | CLIP170 | CYLN1 | RSN | ||||||||||
| Gene Description | CLIP1, CAP-Gly domain containing linker protein 1, is a microtubule binding protein, which regulates cellular polarization and migration, and plays a role in angiogenesis (PMID: 23549612). A CLIP1-ROS1 fusion has been identified in spitzoid neoplasms (PMID: 24445538), a CLIP1-RET fusion has been identified in lung cancer (PMID: 27825636), an FGFR2-CLIP1 fusion has been identified in metastatic cholangiocarcinoma (PMID: 31371345), and overexpression of Clip1 has been identified in breast carcinoma (PMID: 23549612). | ||||||||||
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