Gene Detail

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Gene Symbol CLIP1
Synonyms CLIP | CLIP-170 | CLIP170 | CYLN1 | RSN
Gene Description CLIP1, CAP-Gly domain containing linker protein 1, is a microtubule binding protein, which regulates cellular polarization and migration, and plays a role in angiogenesis (PMID: 23549612). A CLIP1-ROS1 fusion has been identified in spitzoid neoplasms (PMID: 24445538), a CLIP1-RET fusion has been identified in lung cancer (PMID: 27825636), an FGFR2-CLIP1 fusion has been identified in metastatic cholangiocarcinoma (PMID: 31371345), and overexpression of Clip1 has been identified in breast carcinoma (PMID: 23549612).


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