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Gene Symbol BCORL1
Synonyms BCoR-L1 | CXorf10 | SHUVER
Gene Description BCORL1, BCL6 corepressor-like 1, is a transcription corepressor and is involved in histone deacetylase activity (PMID: 17379597). BCORL1 mutations have been observed in acute myeloid leukemia and myelodysplastic syndromes (PMID: 30618304), while elevated expression of BCORL1 has been identified in hepatocellular carcinoma (PMID: 22210327, PMID: 26879601).

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Molecular Profile Protein Effect Treatment Approaches
BCORL1 A1525S unknown
BCORL1 A157T unknown
BCORL1 A257S unknown
BCORL1 - ELF4 loss of function
BCORL1 C1422F unknown
BCORL1 C1573Lfs*2 unknown
BCORL1 D1514Y unknown
BCORL1 D1569V unknown
BCORL1 D1627G unknown
BCORL1 D1627N unknown
BCORL1 D90G unknown
BCORL1 D90Y unknown
BCORL1 E1157K unknown
BCORL1 E1655D unknown
BCORL1 E1685* unknown
BCORL1 E692* loss of function - predicted
BCORL1 G1682Rfs*4 unknown
BCORL1 H993Y unknown
BCORL1 inact mut loss of function
BCORL1 K1207N unknown
BCORL1 L1132I unknown
BCORL1 L1132P unknown
BCORL1 L1538F unknown
BCORL1 L1605R unknown
BCORL1 L84R unknown
BCORL1 L884fs loss of function - predicted
BCORL1 mutant unknown
BCORL1 N1387D unknown
BCORL1 over exp no effect
BCORL1 P1218S unknown
BCORL1 P1681Qfs*20 unknown
BCORL1 P564L unknown
BCORL1 P714T unknown
BCORL1 P968S unknown
BCORL1 Q1076H unknown
BCORL1 Q1076H BRAF V47_D380del BRAF V600E
BCORL1 Q1076H BRAF V600E
BCORL1 Q1133R unknown
BCORL1 Q1191K unknown
BCORL1 R1090* loss of function - predicted
BCORL1 R1224H unknown
BCORL1 R1466W unknown
BCORL1 R1536C unknown
BCORL1 R1548P unknown
BCORL1 R1658K unknown
BCORL1 R1658M unknown
BCORL1 R21C unknown
BCORL1 R639S unknown
BCORL1 R789H unknown
BCORL1 R789L unknown
BCORL1 R945* loss of function - predicted
BCORL1 S1279I unknown
BCORL1 S1563F unknown
BCORL1 S1702F unknown
BCORL1 S210L unknown
BCORL1 S803Y unknown
BCORL1 T345M unknown
BCORL1 T799I unknown
BCORL1 V1096I unknown
BCORL1 V1430I unknown
BCORL1 V1660G unknown
BCORL1 W1468L unknown