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Gene Symbol BID
Synonyms FP497
Gene Description BID, BH3 interacting domain death agonist, interacts with either BAX (to induce cell death) or BCL2 (to antagonize cell death) (PMID: 8918887) and is important in regulating the cross-talk of cell cycle arrest and apoptosis signaling (PMID: 20482490). Increased expression of Bid may play a role in cell transformation and growth in liver cancer (PMID: 27196317, PMID: 25951810).
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