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Gene Symbol PRDM14
Synonyms PFM11
Gene Description PRDM14, PR/SET domain 14, is a transcription factor required for the maintenance of embryonic stem cell identity and the reacquisition of pluripotency in somatic cells (PMID: 20953172, PMID: 31741141, PMID: 31130394). Overexpression and amplification of PRDM14 is associated with various tumor types (PMID: 23690269; PMID: 17942894; PMID: 24249158), including poor prognosis in colorectal cancer patients (PMID: 31741141).
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