Gene Detail


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Gene Symbol BMPR1A
Synonyms 10q23del | ACVRLK3 | ALK-3 | ALK3 | BMPR-1A | CD292 | SKR5
Gene Description BMPR1A, bone morphogenetic protein receptor type IA, is a serine/threonine kinase receptor that activates SMAD signaling pathways, thus regulating transcription of genes involved in growth and development (PMID: 16246179). Germline mutations of BMPR1A are associated with juvenile polyposis syndrome (PMID: 16246179, PMID: 31259752) and BMPR1A variations may be risk factors for gastric cancer (PMID: 31949278).
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