Gene Detail

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Gene Symbol BMPR1B
Synonyms ALK-6 | ALK6 | AMDD | BDA1D | BDA2 | CDw293
Gene Description BMPR1B, bone morphogenetic protein receptor type 1B, is a type I serine/threonine kinase that forms heteromeric complexes with type II receptors, and plays a role in signal transduction (PMID: 27088043, PMID: 26690041). Overexpression of BMPR1B has been identified in breast cancer (PMID: 15892165), and decreased expression in ovarian (PMID: 20587070) and breast cancer (PMID: 26684357, PMID: 19451094, PMID: 15892165), and loss of BMPR1B expression is associated with poorly-differentiated prostate cancer (PMID: 10850425).


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