Gene Detail


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Gene Symbol SMARCA4
Synonyms BAF190 | BAF190A | BRG1 | CSS4 | hSNF2b | MRD16 | RTPS2 | SNF2 | SNF2-beta | SNF2L4 | SNF2LB | SWI2
Gene Description SMARCA4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, is a member of the SWI/SNF family, which regulates transcription through chromatin remodeling (PMID: 27413115). Mutations in Smarca4 have been linked to rhabdoid tumors as well as breast, prostate, lung, pancreas, and colon cancers (PMID: 18437052, PMID: 24145903, PMID: 19234488).
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