Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol SOX9
Synonyms CMD1 | CMPD1 | SRA1 | SRXX2 | SRXY10
Gene Description SOX9, SRY-box 9, is an HMG box transcription factor which plays a crucial role in chondrogenesis, organogenesis, and neural crest development (PMID: 22246670). Overexpression of Sox9 has been observed in cancers of the skin, prostate, lung, colon, and brain, while decreased expression has been reported in melanoma (PMID: 22246670, PMID: 28988015, PMID: 30675295, PMID: 30642390).
Additional content available in CKB BOOST