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|Synonyms||BPES | BPES1 | PFRK | PINTO | POF3|
|Gene Description||FOXL2, forkhead box L2, encodes for a transcription factor that is a member of the forked-winged helix family and plays a role in ovary development (PMID: 21640373). FOXL2 is commonly mutated in granulosa-cell tumors (PMID: 19956657, PMID: 31162286), including of the ovary (PMID: 32064045).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FOXL2 C134W||granulosa cell tumor||not applicable||N/A||Preclinical||Diagnostic||FOXL2 C134W mutations are used in the diagnosis of adult granulosa cell tumors of the ovary (PMID: 26791928, PMID: 22240241).||26791928 22240241|