Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol STK3
Synonyms KRS1 | MST2
Gene Description STK3, serine/threonine kinase 3, is a member of the mammalian sterile twenty (MST) kinase family (PMID: 30882881) and is activated by caspases to promote DNA fragmentation during apoptosis (PMID: 29876001) and may play a role in the innate immune response (PMID: 28757478). Stk3 functions as a putative tumor suppressor within the Hippo pathway through YAP1 to regulate cell proliferation (PMID: 15994916, PMID: 24336504, PMID: 29876001), and may also promote tumorigenesis in other tumor types (PMID: 29876001).
Additional content available in CKB BOOST