Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||KRS1 | MST2|
|Gene Description||STK3, serine/threonine kinase 3, is a member of the mammalian sterile twenty (MST) kinase family (PMID: 30882881) and is activated by caspases to promote DNA fragmentation during apoptosis (PMID: 29876001) and may play a role in the innate immune response (PMID: 28757478). Stk3 functions as a putative tumor suppressor within the Hippo pathway through YAP1 to regulate cell proliferation (PMID: 15994916, PMID: 24336504, PMID: 29876001), and may also promote tumorigenesis in other tumor types (PMID: 29876001).|