Gene Detail


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Gene Symbol STK3
Synonyms KRS1 | MST2
Gene Description STK3, serine/threonine kinase 3, is a serine/threonine protein kinase activated by caspases to promote DNA fragmentation in apoptosis and functions as a putative tumor suppressor within the HIPPO pathway through YAP1 to regulate cell proliferation and organ size (PMID: 15994916, PMID: 24336504, PMID: 29876001), but may also promote tumorigenesis in other tumor types (PMID: 29876001).

Additional content available in CKB BOOST