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Gene Symbol SUV39H1
Synonyms H3-K9-HMTase 1 | KMT1A | MG44 | SUV39H
Gene Description SUV39H1, suppressor of variegation 3-9 homolog 1, is a H3K9me3-specific histone methyltransferase (PMID: 32061753) that regulates transcription through chromatin modification and plays a role in cell cycle and differentiation (PMID: 12723694, PMID: 28106510). Dysregulated SUV39H1 expression has been associated with genomic instability in chronic lymphocytic leukemia (PMID: 28833505) and overexpression has been observed in colorectal carcinoma (PMID: 32061753).
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