Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol TAF1
Synonyms BA2R | CCG1 | CCGS | DYT3 | DYT3/TAF1 | KAT4 | MRXS33 | N-TAF1 | NSCL2 | OF | P250 | TAF(II)250 | TAF2A | TAFII-250 | TAFII250 | XDP
Gene Description TAF1, TATA-box binding protein associated factor 1, is a major component of the transcription factor II D (TFIID) complex that has histone acetyltransferase and kinase activities (PMID: 8980232, PMID: 8625415), regulates expression of genes involved in cell cycle and apoptosis (PMID: 10716982). TAF1 mutations have been identified in uterine serous carcinoma (PMID: 23359684), gastric, colorectal (PMID: 27571988), and clear cell endometrial cancer (PMID: 28485815).
Additional content available in CKB BOOST