Gene Detail

Gene Symbol TARBP2
Synonyms LOQS | TRBP | TRBP1 | TRBP2
Gene Description TARBP2, TAR (HIV-1) RNA binding protein 2, functions as part of the RNA induced silencing complex (RISC) to regulate siRNA mediated gene silencing and as an inhibitor of PKR (PMID: 25437560). Mutations in Tarbp2 have been detected in gastrointestinal cancers and overexpression has been detected in breast cancer (PMID: 22719182, PMID: 24563327).
Entrez Id 6895
Chromosome 12
Map Location 12q13.13
Canonical Transcript NM_134323


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