Gene Detail

Gene Symbol TCF7L2
Synonyms TCF-4 | TCF4
Gene Description TCF7L2, transcription factor 7-like 2 (T-cell specific, HMG-box), is a HMG box-containing transcription factor which regulates the Wnt signaling pathway, as well as modulating MYC expression (PMID: 18177486, PMID: 9727977). Mutations in Tcf7l2 has been found in colorectal cancers (PMID: 10919662)
Entrez Id 6934
Chromosome 10
Map Location 10q25.2-q25.3
Canonical Transcript XM_005270084


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