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Gene Symbol BTK
Synonyms AGMX1 | AT | ATK | BPK | IGHD3 | IMD1 | PSCTK1 | XLA
Gene Description BTK, Bruton tyrosine kinase, is a non-receptor tyrosine kinase involved in B-cell activation and development (PMID: 24658273). BTK is commonly overexpressed in various hematological malignancies (PMID: 24658273) and BTK mutations have been linked to BTK inhibitor drug resistance (PMID: 28235842).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
695 X Xq22.1 NM_000061 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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