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Gene Symbol TEAD1
Synonyms AA | NTEF-1 | REF1 | TCF-13 | TCF13 | TEAD-1 | TEF-1
Gene Description TEAD1, TEA domain transcription factor 1, is a transcription factor which functions through the YAP1-Hippo pathway to regulate cell proliferation and apoptosis (PMID: 18579750, PMID: 26805820). Abnormal expression of Tead1 has been identified in several cancers including prostate, pancreatic, breast, and bladder (PMID: 23029054) and a TEAD1-NCOA2 fusion has been identified in spindle cell rhabdomyosarcoma (PMID: 23463663, PMID: 31999033).
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