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Gene Symbol TFE3
Synonyms bHLHe33 | RCCP2 | RCCX1 | TFEA
Gene Description TFE3, transcription factor binding to IGHM enhancer 3, is a transcription factor that plays a role in developmental and cellular processes, including targeting genes downstream of TGF-beta signaling (PMID: 15118077). TFE3 fusions are commonly associated with renal cell carcinoma (PMID: 29713041, PMID: 30622287, PMID: 24455396), perivascular epithelioid cell tumors (PMID: 26975036, PMID: 31309284), alveolar soft-part sarcoma (PMID: 30347044), and epithelioid hemangioendothelioma (PMID: 32151991).

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