Gene Detail

Gene Symbol TFE3
Synonyms bHLHe33 | RCCP2 | RCCX1 | TFEA
Gene Description TFE3, transcription factor binding to IGHM enhancer 3, is a transcription factor that plays a role in developmental and cellular processes, including targeting genes downstream in TGF-beta signaling (PMID: 15118077). TFE3 fusions are commonly associated with renal cell carcinoma and perivascular epithelioid cell tumors (PEComas) (PMID: 26975036, PMID: 24455396).
Entrez Id 7030
Chromosome X
Map Location Xp11.23
Canonical Transcript NM_006521

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