Gene Detail


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Gene Symbol TGFB1
Synonyms CED | DPD1 | IBDIMDE | LAP | TGF-beta1 | TGFB | TGFbeta
Gene Description TGFB1, transforming growth factor beta 1, is a secreted cytokine that regulates cell growth, proliferation, differentiation, and apoptosis (PMID: 3861940). Altered Tgfb1 expression has been demonstrated in a variety of tumor types (PMID: 20001556), including head and neck squamous cell carcinoma (PMID: 32118031), and elevated Tgfb1 levels have been reported in the urine from muscle invasive and high-grade urothelial carcinoma patients (PMID: 31514337).
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