Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol TGFB1
Synonyms CED | DPD1 | IBDIMDE | LAP | TGF-beta1 | TGFB | TGFbeta
Gene Description TGFB1, transforming growth factor beta 1, is a secreted cytokine that regulates cell growth, proliferation, differentiation, and apoptosis (PMID: 3861940). Altered Tgfb1 expression has been demonstrated in a variety of tumor types (PMID: 20001556), including head and neck squamous cell carcinoma (PMID: 32118031), and elevated Tgfb1 levels have been reported in the urine from muscle invasive and high-grade urothelial carcinoma patients (PMID: 31514337).
Additional content available in CKB BOOST