Gene Detail

Gene Symbol TGFBR2
Synonyms AAT3 | FAA3 | LDS1B | LDS2 | LDS2B | MFS2 | RIIC | TAAD2 | TBR-ii | TBRII | TGFbeta-RII | TGFR-2
Gene Description TGFBR2, transforming growth factor, beta receptor II, is a membrane bound Ser/Thr protein kinase that heterodimerize with Tgfbr1 to meidate Tgf beta signaling (PMID: 15270668). Mutations or abnormal expression of Tgfbr2 have been reported in colon and pancreatic cancers (PMID: 15256431, PMID: 25060520).
Entrez Id 7048
Chromosome 3
Map Location 3p24.1
Canonical Transcript NM_003242

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