Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | TMPRSS2 | ||||||||||
| Synonyms | PRSS10 | ||||||||||
| Gene Description | TMPRSS2, transmembrane protease,serine 2, is a member of the type II transmembrane serine protease that is regulated by androgen (PMID: 26018085) and plays a role in viral spread, including coronaviruses (PMID: 30626688). TMPRSS2 fusions frequently occur with ETS transcription factors, including ERG and ETV1, and are commonly observed in prostate cancer (PMID: 20478527, PMID: 30680235, PMID: 31900904, PMID: 31915468). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
