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| Gene Symbol | TRAF2 | ||||||||||
| Synonyms | MGC:45012 | RNF117 | TRAP | TRAP3 | ||||||||||
| Gene Description | TRAF2, TNF receptor associated factor 2, is an adaptor protein that functions in activation of NF-kappaB and JNK signaling, and plays a role in regulation of apoptosis (PMID: 11875461, PMID: 24362534). TRAF2 amplification has been observed in several tumor types including colorectal, breast, and lung cancers (PMID: 24362534). | ||||||||||
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