Gene Detail

Gene Symbol TRAF3
Synonyms CAP-1 | CAP1 | CD40bp | CRAF1 | IIAE5 | LAP1 | RNF118
Gene Description TRAF3, TNF receptor-associated factor 3, is a key regulator of NF-KappaB signaling through ubiquitin-dependent degradation, therefore regulates lymphocytes function and survival, and tumorigenesis (PMID: 26085207). Inactivation of TRAF3 has been identified in multiple myeloma and lymphoma (PMID: 26085207).
Entrez Id 7187
Chromosome 14
Map Location 14q32.32
Canonical Transcript NM_003300


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