Gene Detail

Gene Symbol TTN
Synonyms CMD1G | CMH9 | CMPD4 | EOMFC | HMERF | LGMD2J | LGMDR10 | MYLK5 | SALMY | TMD
Gene Description TTN, titin, is a large protein filament that is a major component of the sarcomere, and plays mechanical, organizational, and signaling roles in cardiac and skeletal muscle (PMID: 21257761). TTN has been demonstrated to be frequently mutated in several tumor types (PMID: 17344846, PMID: 18085994).
Entrez Id 7273
Chromosome 2
Map Location 2q31.2
Canonical Transcript NM_001256850


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