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Gene Symbol TXN
Synonyms TRDX | TRX | TRX1 | Trx80
Gene Description TXN, thioredoxin, encodes for an antioxidant protein that plays a role in a variety of cellular functions including cell growth, survival, and apoptosis (PMID: 21453190, PMID: 32097513). TXN overexpression has been observed in several tumor types such as hepatocellular carcinoma, osteosarcoma, and melanoma (PMID: 28011619), and is associated with chemoresistance in squamous cervical carcinoma (PMID: 31470801).
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