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Gene Symbol TYR
Synonyms ATN | CMM8 | OCA1 | OCA1A | OCAIA | SHEP3
Gene Description TYR, tyrosinase, is a type I membrane bound glycoprotein and a copper-dependent enzyme that catalyzes the hydroxylation and oxidation steps of melanin biosynthesis, and regulates melanogenesis (PMID: 23539007, PMID: 19735457, PMID: 12028580). TYR expression has been identified in melanoma (PMID: 12088451, PMID: 8722221).
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