Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Gene Description||VAV2, vav guanine nucleotide exchange factor 2, is a member of the Dbl protein family activated by Egf and Pdgf that acts as a guanine nucleotide exchange factor for Rho family GTPases (PMID: 10744696, PMID: 11448999), and is involved in cell migration (PMID: 10982832), lamellipodia formation (PMID: 11448999, PMID: 10982832), and cell spreading (PMID: 11448999). VAV2 overexpression has been identified in gastric cancer (PMID: 28459214).|