Gene Detail

Gene Symbol WEE1
Synonyms WEE1A | WEE1hu
Gene Description WEE1, WEE1 G2 checkpoint kinase, is a tyrosine kinase that phosphorylates and inactivates the Cdk1-cyclin B comples, resulting in cell cycle arrest which allows DNA repair (PMID: 27427153). Altered Wee1 expression level has been reported in various cancers (PMID: 27427153).
Entrez Id 7465
Chromosome 11
Map Location 11p15.4
Canonical Transcript NM_003390

Additional content available in CKB BOOST