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Gene Symbol XRCC2
Synonyms FANCU
Gene Description XRCC2, X-ray repair cross complementing 2, is an XRCC gene family member and a RAD51 paralog (PMID: 31275435) that is involved in homologous recombination repair (PMID: 15279796). XRCC2 variants may confer increased cancer risk in a variety of cancers including, breast and skin cancers (PMID: 15723711), and increased expression has been associated with decreased survival in hepatocellular carcinoma (PMID: 32258128).


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