Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||DELTA | GADEVS | INO80S | NF-E1 | UCRBP | YIN-YANG-1|
|Gene Description||YY1, YY1 transcription factor, is a zinc-finger transcription factor that regulates expression of genes involved in biological processes including cell growth, proliferation, and differentiation (PMID: 16611997, PMID: 20081375). Dysregulation of YY1 is associated with several tumor types including, nasopharyngeal carcinoma (PMID: 30718276), YY1 mutations are recurrent in insulinoma (PMID: 20081375, PMID: 25787250) and an EWSR1-YY1 fusion has been identified in mesothelioma (PMID: 23630070).|