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Gene Symbol DDR1
Synonyms CAK | CD167 | DDR | EDDR1 | HGK2 | MCK10 | NEP | NTRK4 | PTK3 | PTK3A | RTK6 | TRKE
Gene Description DDR1, discoidin domain receptor tyrosine kinase 1, encodes for a tyrosine kinase receptor that is activated by collagen and plays a necessary role in the development of mammary glands (PMID: 24671415). DDR1 overexpression and DDR1 mutations have been associated with a variety of cancers including lung (PMID: 31659178), leukemia (PMID: 21398698), melanoma (PMID: 31271515), ER-positive breast cancer (PMID: 30181556), and metastatic colon cancer (PMID: 32117772).


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