Gene Detail


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Gene Symbol VTCN1
Synonyms B7-H4 | B7h.5 | B7H4 | B7S1 | B7X | PRO1291 | VCTN1
Gene Description VTCN1, V-set domain containing T cell activation inhibitor 1, is a member of the B7-family proteins that regulates immune response and tumor microenvironment (PMID: 28258701) and is an inhibitory immune checkpoint protein (PMID: 31555486, PMID: 31677920). VTCN1 overexpression has been identified in a wide variety of tumors (PMID: 28258701), including pancreatic cancer (PMID: 31282407), ovarian cancer (PMID: 31128028), and colorectal cancer (PMID: 30363700).
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